Research is focused on the evaluation of CNS acting compounds that are potentially neurotoxic to the developing CNS or have therapeutic potential. Additional research interests encompass the development of animal models of human neurobiological disorders, especially those disorders with a suspected developmental origin.
Research Interests:
Developmental neurotoxicology
Animal models
CNS
Learning and memory
Amino acids
Citations:
Title: Persistent changes in learning and memory in rats following neonatal treatment with domoic acid Author(s): Adams, AL; Doucette, TA; James, R, et al. Source: PHYSIOLOGY & BEHAVIOR Volume: 96 Issue: 4-5 Pages: 505-512 Published: 2009
Title: Effects of estrous stage and time of day on prepulse inhibition in female rats
Title: Altered responses to novelty and drug reinforcement in adult rats treated neonatally with domoic acid
Title: Hippocampal mossy fiber sprouting and elevated trkB receptor expression following systemic administration of low dose domoic acid during neonatal development
Title: An improved post-operative care protocol allows detection of long-term functional deficits following MCAo surgery in rats Author(s): Ryan, CL; Doucette, TA; Gill, DA, et al. Source: JOURNAL OF NEUROSCIENCE METHODS Volume: 154 Issue: 1-2 Pages: 30-37 Published: JUN 30 2006
