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Tarek Saleh

  • B.Sc., University of Western Ontario, 1992
  • Ph.D., University of Western Ontario, 1995
Professor & Chair, Chief Scientific Officer, ACBV
Biomedical Sciences
Veterinary Medicine
(902) 566-0819
Research Interests: 
    • Central Regulation of Autonomic Function
    • Application of electrophysiological and neuroanatomical techniques to investigate the role of central autonomic regulatory nuclei in the control of blood pressure and heart rate
    • Investigating the role of peptides (such as substance P, neurotensin, cholecystokinin, somatostatin and calcitonin gene-related peptides) and hormones (estrogen) in modulating neuronal responses in cardiovascular nuclei to visceral afferent activation
    • Investigating the involvement of neurochemicals and neurohormones in autonomic nuclei which have been implicated in the central component of the baroreflex in health and disease
    • Investigating the role of hormones in functional neuroprotection from neurodegenerative diseases such as stroke, Alzheimer Disease, and spinal cord injury

Wilson, B.C., Milne P and Saleh TM. Relaxin pretreatment reduces infarct size in male rats following middle cerebral artery occlusion. Annals NY Acad Sci, 1041:1-6, 2005.

Saleh, T.M., B.J. Connell, and A.E. Cribb. Sympathoexcitatory effect of estrogen in the insular cortex is modulated by GABA. Brain Res., 1037(1- 2):114-122, 2005.

Saleh, T.M., B.J. Connell, C. Legge and A.E. Cribb. Stroke-induced neurochemical changes in the central nucleus of the amygdala of male rats. Neuroscience, 135(4):1141-1153, 2005.

Fatehi, M., Saleh, T.M. and Kombian, S.B. Estrogen attenuates a potassium conductance in parabrachial neurons in vitro. Neuroscience, 135(4):1075- 1086, 2005.

Saleh TM, Connell, BJ and Cribb AE. Estrogen in the parabrachial nucleus reduces the sympathoexcitatory effect following MCAO in male rats. Brain Res., 1066; 187-195, 2005.

Wilson, B.C., Connell, B and Saleh TM. Relaxin-induced decrease in infarct size in male rats is dependent on NO synthase and not estrogenic mechanisms. Neurosci. Lett., 393-160-164, 2006.

Cribb, AE, Knight, J, Tesch M, Dryer, D, Guernsy, J and Saleh TM. Role of polymorphic human cytochrome P450 enzymes in estrone oxidation. Cancer Epidemiology, Biomarkers & Prevention., 15; 551-558, 2006.

Webb, AA., Chan, CB., Brown, A., and Saleh TM. Estrogen reduces the severity of autonomic dysfunction in spinal cord-injured male mice. Behav Brain Res., 171:338-349, 2006.

Fatehi, M., Zidichouski, J., Kombian, S.B., and Saleh, T.M. Estrogen attenuates excitatory neurotransmission in rat parabrachial neurons in vitro. J. Neurosci. Res., 84:666-674, 2006.

Current Collaborators (non-UPEI): 
  • Brian Wilson, Acadia University
  • Gary Allen, Dalhousie University
  • Sam Kombian, University of Kuwait
  • Michael Mayne, NRC-INH